How to Get Potent Medicine in Persona 3 Reload

Persona 3 Reload: How to Find Potent Medicine

Elizabeth is fascinated by the human world and will make numerous requests to the protagonist in Persona 3 Reload. At one point, she will ask for Potent Medicine.

Persona 3 Reload Potent Medicine Location

To fulfill Elizabeth’s Request number 20, you’ll need to locate a strange drug known as Potent Medicine. Unfortunately, the Velvet Room attendant won’t provide any hints about the location of this item, which may leave players confused after being unable to find it at Aohige Pharmacy.

Unlike regular drugs, Potent Medicine cannot be purchased from shops as it’s a special concoction created by Mr. Edogawa. You can meet this teacher after school in the Nurse’s Office on the first floor of Gekkoukan High School.

Image Source: Atlus viaTwinfinite

Although Mr. Edogawa is reluctant to give you this drug initially, he eventually relents after you claim it’s for an emergency. Once you have the item, you can travel to Paulownia Mall and enter the hidden alley where the Velvet Room’s entrance stands.

After consuming the Potent Medicine, Elizabeth will comment on its taste and give you a one-handed sword called Steel Pipe for the protagonist, which has the following stats:

  • Attack: 110
  • Accuracy: 85
  • Effect: +Confuse (high)

You can also consume the drug yourself by visiting the Nurse’s Office. Despite rumors about its lethality, the drug is completely safe and grants one point for Courage when consumed. Additionally, you don’t have to spend your afternoon attempting this challenge, and you can use it to hang out with your companions, such as Yuko.

That’s everything you need to know about how to obtain Potent Medicine in Persona 3 Reload. For more content related to Persona 3 Reload, you can check out our guide on how to increase your Charm.

About the author

Gabriela Jessica

Gabriela has been a Freelance Writer for Twinfinite since 2023. She mainly covers Genshin Impact but also enjoys trying out new games. Her favorites are TOTK, Stardew Valley, RDR2, The Witcher 3, and RE4 Remake. Gabriela has a BA in English Literature from Ma Chung University and loves to spend her time reading novels and manga/anime.